Today, December 28 of the current year, the Latin American Institute of Biotechnology MECHNIKOV made a contribution to the Ministry of Health of the Republic of Nicaragua (MINSA) in the amount of 20 thousand doses of the fractionated inactivated influenza vaccine.

The delivery to Health Ministery of Nicaragua made by the MECHNIKOV Institute is also a contribution in the fight against COVID-19, since the wide application of influenza vaccines is considered important due to the early diagnosis of coronavirus infection and the innate immunity that it supposedly produces.

The MECHNIKOV Institute is the only plant in Central America that produces this type of vaccine, thus guaranteeing its distribution both in Central American countries and in other Latin American countries. Located in the Republic of Nicaragua, the Institute is able to supply a large number of countries with vaccines.

Round Table

In the framework of the Conference organized by the Ministry of Industry and Trade of the Russian Federation together with the State Institute of Medicines and Good Practices, the General Manager of the Institute
MECHNIKOV Stanislav Uiba made a presentation on the Institute’s experience during the GMP Certification and Registration process by the Center for State Control of Medicines, Medical Equipment and Devices (CECMED) of Cuba.

The round table dealt with specific aspects of the process and the collaboration between both institutions, and special attention was paid to accompanying CECMED in the Prequalification process of the Institute’s fractionated inactivated influenza vaccine (VAIF) before the WHO.


In past years, this Conference has received representatives of the global pharmaceutical community from Russia, the United States, Austria, Spain, Japan, Switzerland, Italy, Mexico, Great Britain, Cuba, Germany, Brazil and other countries. Conference partners are leading Russian and international companies, major industry players and professional communities.


Each year, the event takes place in a new region of Russia, helping organizers to demonstrate good practices in various parts of the country and to familiarize participants with the regional aspect of organizing the health system and providing medicines.

On June 25, at the age of 67, pased away Dr. Rafael Pérez Cristiá, Director of the Center for the State Control of Medicines, Equipment and Medical Devices (CECMED), Doctor of Medical Sciences, Head of the Academy of Sciences of Cuba.

The collaborators of the MECHNIKOV Institute mourn their irreparable loss and wish to extend their sincere condolences to the family and friends of the great man and scientist, who was the first to proclaim the thesis that Regulatory Authorities should be developed following the developers and manufacturers of medicines modern, and not limit with its inflexibility and instructions to a world that changes rapidly and requires the introduction of new drugs in practice.

Dr. Rafael Pérez headed CECMED in 1999. The contribution of his knowledge to the strengthening of the drug regulatory policy in Cuba contributed to the categorization of CECMED as the National Regulatory Authority of Reference Medicines of PAHO for the Americas and National Regulatory Authority of Vaccines certified by WHO.

Dr. Pérez will forever remain in the history of Institute MECHNIKOV as one of the founding fathers, because it was largely, thanks to his efforts, that we were able to carry out the project of our Institute and complete the transfer of technology for the production of vaccines against the flu.

Dr. Pérez lived a brilliant and active life, he was distinguished for his deep humanity, genuine intelligence, high professionalism, love for life and optimism.

Today all the collaborators of the MECHNIKOV Institute are with the family of Dr Pérez and all Cuban citizens. The memory of Rafael Pérez will remain forever in our hearts.

A Companion. A Friend. A Teacher.

The Russian offer may be the best option for Latin America in the face of the coronavirus. The country has an advanced biotechnology industry and successful international experience. In this context, the Latin American Institute of Mechnikov Biotechnology [ILBM], a vaccine plant installed in Nicaragua with Russian technology, is an exemplary case.

Its general manager, Stanislav Uiba, indicated in conversation with Radio Sputnik that the innovative center – whose headquarters is the Scientific Research Institute of Vaccines and Serums of Saint Petersburg – will have in the medium term a vaccine that will guarantee immunity against COVID- 19, the result of “a fairly aggressive program” that is being carried out “at this time” to develop a definitive solution to the disease.

He reported that by this month of August there will be “at least three vaccine candidates” against the coronavirus, that is, “they have passed the preclinical studies with success.”

Meanwhile, ILBM is already contributing to the public health of the region, its “main and initial product” being the influenza vaccine that activates immune mechanisms that not only fight the flu, but also make the organism more resistant to other diseases. infectious, including the coronavirus.

In addition to Nicaragua, the regional countries that are already receiving the vaccine are Cuba, Ecuador and Venezuela, with concrete steps to expand the geographic scope of supplies, a strategy that has the support of the National Committee for Economic Collaboration with the Countries of Latin America , a Moscow-based entity that is in charge of promoting ties between the parties.

“We also have other development vectors distributing other vaccines of interest here in Latin America, for example, against yellow fever, hepatitis or rotavirus,” he added.

“What Russia offers is pharmaceutical products – in this case vaccines – of the highest quality, meeting all international requirements. And they are also products at affordable prices,” Stanislav Uiba said.

Audio in Spanish

https://sptnkne.ws/CrW2

Vaccination 2020

The Latin American Institute of Biotechnology MECHNIKOV, on May 4 of this year, carried out a vaccination program against influenza for its collaborators and their families with the same vaccine manufactured by the Institute.

Preventive vaccination against Flu allows minimizing the risks of co-infection both in medical personnel and in risk groups, which coincide with the risk groups most affected by COVID-19. Reducing the burden of influenza virus infection on the health system and economies allows these resources to be dedicated to the fight against other diseases in the current global situation.

The WHO document “Guidelines for immunization during the COVID-19 epidemic” issued on March 26 of this year, points out the importance of preventive vaccination against influenza.

In the same way, masks are being used and the temperatures of employees and visitors are being mesured. Taking hygiene measures with hand washing, applying alcohol and cleaning the place with disinfectants at all times is a primary need in the current situation. We thank all the collaborators of the MECHNIKOV Institute for complying with hygiene and safety measures, and it is hoped that in this way we can protect ourselves against COVID-19.

Vaccination day in Nicaragua

Latin American Institute of Biotechnology MECHNIKOV delivered 600,000 doses of the influenza vaccine to the Nicaraguan Ministry of Health for the vaccination session.
The MECHNIKOV Institute guarantees the delivery of vaccines in thermal boxes with cold accumulators to guarantee the quality of the product in the temperature range required for its transportation from our plant to the MINSA facilities.

Russia collaborated in the delivery of 8,000 doses of Interferon Alpha 2B – a drug planned to be used against the Coronavirus – to Nicaragua, the St. Petersburg Institute for Scientific Research on Vaccines and Serums told TASS on Friday.


Interferon Alpha 2B was delivered to Nicaragua from Cuba with logistical coordination from the Latin American Institute of Biotechnology MECHNIKOV, a Russian-Nicaraguan JV manufacturer of biological drugs. The press service of the Institute of Vaccines and Serums of Saint Petersburg pointed out that considering the international situation this supply is significant for both Cuba and Nicaragua.


“We have responded to the request of our Cuban colleagues and developed the logistics of delivery of our influenza vaccine to Cuba in a way that allowed us to dispatch the Interferon on the same plane, which the people of Nicaragua need at this time,” said the director of the Mechnikov Institute, Stanislav Uiba.


Interferon has been recommended for COVID-19 patients in a number of countries, including Russia. The fifth edition of the temporary methodical recommendations on the prevention, diagnosis and treatment of coronavirus was published on Thursday. According to this document, Interferon Alpha 2B has anti-inflammatory, antiviral and immunomodulatory effects. According to the Russian Ministry of Health, the effects of the drug are based on “preventing the recurrence of viruses that enter the human body through the respiratory tract.”
According to statistics from the World Health Organization, Nicaragua has 6 registered cases of coronavirus as of April 10, 2020.
Original information https://tass.com/world/1142939

The executive president of the Nicaraguan Institute of Social Security (INSS), Roberto López, reported this Thursday that Interferon Alpha 2B, a Cuban drug that is used within the spectrum of drugs to treat patients infected by coronavirus, could begin to be produced in Nicaragua .

López, made a tour of the Mechnikov vaccine plant (Managua) together with the deputy director of the Center for Genetic Engineering and Biotechnology (CIGB) of Cuba, Marta Ayala. Both specialists valued the possibility of starting the preparation process for the production of the Cuban medicine.

Ayala, expressed that the visit is an expression of solidarity and brotherhood among the peoples of Latin America to share knowledge and fight together the coronavirus pandemic. “We think that from the governments, the authorities, we must be prepared for this epidemic, for which each one of the citizens must be very active, investigating ourselves, alerting but also preparing ourselves, therapeutically speaking, to be able to care for the sick that may arise” , he assured.

The intention of both governments is to have a retroviral production capacity in the Central American country to attend to its patients and at the same time function as the closest point of sale to the rest of the countries in the region under the operations of the Grupo de las Industrias Biotechnology and Pharmaceutical of Cuba (BioCubaFarma).

Russian delegation visits MECHNIKOV vaccine plant.
The Vice President of the State Duma of the Russian Federation, Olga Epifánova, visited the Latin American Institute of Biotechnology MECHNIKOV this Wednesday, December 11, as part of its activities framed by the celebration of the 75th Anniversary of the establishment of diplomatic relations of friendship, brotherhood and solidarity between Russia and Nicaragua.


“For me it has been very important to have come to this Institute that is made with the collaboration of our Federal Medico-Biological Agency, because for me, we can say, it is as if it were the first international swallow. It was very interesting to see, what are the plans, because Latin America is far from Russia and here we see another picture in terms of diseases, “said Epifánova.


During the visit he was able to learn about the operation and projections of the plant, since he is responsible for the Health Committee which allows him to be in contact with the medical society and be aware of what is happening in this area in Russia and abroad. she.


Epifánova stated that the Institute has the best technology, which opens opportunities for Nicaraguan personnel to obtain the best knowledge from Russian specialists.


“Young people in this country have the possibility of working with these technologies. It is a very great possibility for them,” Epifánova explained.

Meeting in Guatemala

Guatemala City, September 25, 2019. The Executive Secretary of SE-COMISCA, Dr. Alejandro Solís Martínez and the Technical Assistant for the COMISCA Joint Negotiation Process, Licda. Margarita García, hold a tripartite meeting with delegates from the Mechnikov Vaccine Institute and the Federal Medical-Biological Agency of Russia to explore the feasibility of the regional project for the production of blood products and safe blood, solutions for hemodialysis and insulin with the aspiration that this initiative be become a Community Regional Public Good.

The Executive Secretariat of COMISCA continues to work so that the benefits of regional integration in health reach our people through strategic alliances with new partners that support regional development.

On August 5, 2019, the Ministry of Health launched the second day of vaccination against influenza in Nicaragua with the vaccine manufactured at the MECHNIKOV Institute plant in Managua, Nicaragua.

MINSA during the day will apply 600 thousand doses to the Nicaraguan population 6 years of age and over.

The flu vaccination day begins on August 5 and will last until September 28.

The start-up of the industrial-scale production lines was held in the presence of the investment advisor of the Nicaraguan Government, colleague Laureano Ortega, the Vice Minister of Health of the Russian Federation, Sergey Kraevoy, the President of the Nicaraguan Institute of Social Security, Dr. Roberto López, the Director of the Federal Medical-Biological Agency of Russia (AFMB), Dr. Vladimir Uiba and the Director of the St. Petersburg Institute for Scientific Research of Vaccines and Serums of the AFMB of Russia (IICVSSP) , Víctor Trukhín.

The MECHNIKOV Institute has become a new stage of cooperation between Russia and Latin American countries and a new brand with the participation of Russia in Central America, which opens up unique opportunities to improve the level of sanitation throughout the region. The project was implemented in close collaboration with and with the support of the Pan American Health Organization (PAHO).

Vaccine production in Managua has been created in record time. According to UNIDO, the complete cycle from the structural design of a plant of this type to the start-up in the conditions of developing countries can take up to 7 years. The construction of the industrial complex of the MECHNIKOV Institute was completed in less than a year, in October 2016. It took more than two years to provide modern equipment, complete qualification procedures for critical engineering facilities and systems, validate technological processes in the framework of technology transfer and validating the transportation of the finished product complying with the “cold chain” from Russia to Nicaragua and from Nicaragua to Cuba. In 2018, the certification of compliance with the GMP requirements took place, carried out by the Cuban Regulatory Authority CECMED, which has a higher evaluation (level four) according to the PAHO scale.

Another equally important and complicated process for both time and resources consisted of registering the Russian influenza vaccine in Cuba and Nicaragua, with the subsequent supply of the pharmaceutical product and its application in the vaccination of the population of these countries.

The largest producers of influenza vaccines are present in the markets of Latin American countries, including the French Sanofi Pasteur, the English GSK and the South Korean Green Cross, as well as local producers from Brazil, Mexico and Argentina.

Today, the MECHNIKOV Institute is the only biotechnology company in Central America and has the status of a regional producer.

Taking into account that the level of social support received by the population of Latin America is high, the public health sector of most of the countries in this region is interested in long-term cooperation, based on purchasing a sufficient quantity of pharmaceutical products. at fixed prices. The MECHNIKOV Institute plans to market its products, including the influenza vaccine, at a competitive price determined based on the quantities supplied and the terms of the contracts that are signed.

From now on, it is planned to carry out the technology transfer of other immunobiological products on the MECHNIKOV Institute platform.


Dr. Vladímir Uiba

The Head of the AFMB of Russia, Dr. Vladimir Uiba points out that the development of the MECHNIKOV Institute will have three main lines. In the first place, it is a matter of producing the influenza vaccine and multiplying its commercial outlets. In addition, the MECHNIKOV Institute will guarantee the transfer of technology for the manufacture of relevant pharmaceutical products in the region, including the vaccine against hepatitis A and recombinant erythropoietin, produced by the State Institute for Scientific Research on Highly Purified Biopreparations. Another line of development will be the carrying out of research in the most diverse fields, as well as the preparation of human resources and the professional guidance of youth, in particular, within the framework of the BioNICA project..